Emraclidine, CAS 2170722-84-4

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: 1-(5,7-dihydro-2,4-dimethyl-6H-pyrrolo[3,4-b]pyridin-6-yl)-2-[1-[2-(trifluoromethyl)-4-pyridinyl]-3-azetidinyl]-ethanone

Purity: ≥98%

Formula Markup: C20H21F3N4O

Formula Weight: 390.4

CAS Number: 2170722-84-4

Notes: An M4 muscarinic receptor PAM; selective for M4 mAChRs over a panel of 59 receptors, ion channels, transporters, and enzymes at 10 µM; selectively potentiates ACh-induced activation of the M4 mAChR over M1-M3 and M5 mAChRs in cells expressing the human receptors (EC50s = 12.3, 4,798, >10,000, >10,000, and >10,000 nM, respectively); inhibits amphetamine-induced locomotor activity in mice and prepulse inhibition deficits in rats at 3.2 mg/kg

• SKU: CAY42125-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 42125-5
• Package Unit: 5 mg
• Quantity Unit: STK