EN4, CAS 1197824-15-9

Product Description: EN4 is a covalent ligand that targets cysteine 171 (C171) of MYC. EN4 is selective for c-MYC over N-MYC and L-MYC. EN4 inhibits MYC transcriptional activity, downregulates MYC targets, and impairs tumorigenesis[1].

Applications: Cancer-programmed cell death

Formula: C25H24N2O4

References: [1]Lydia Boike, et al. Discovery of a Functional Covalent Ligand Targeting an Intrinsically Disordered Cysteine within MYC. Cell Chem Biol. 2021 Jan 21;28(1):4-13.e17.

CAS Number: 1197824-15-9

Molecular Weight: 416.47

Compound Purity: 97.05

Research Area: Cancer

Solubility: DMSO : 125 mg/mL (ultrasonic)

Target: c-Myc

• SKU: MEXHY-134761-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-134761-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK