Enpp1 Polyclonal Antibody

Enpp1 Polyclonal Antibody
SKU
ELSE-AB-91948-200
Packaging Unit
200μL
Manufacturer
Elabscience Biotechnology

Availability: loading...
Price is loading...
Target Synonym: Pca;ttw;twy;M6S1;NPP1;Npps;PC-1;Ly-41;Pca-1;Pdnp1;C76301;CD203c;E-NPP1;E-NPP 1;AI428932;4833416E15Rik;Enpp1

Storage: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Background: This gene encodes a member of the nucleoside pyrophosphatase/phosphodiesterase family of enzymes that catalyzes the hydrolysis of pyrophosphate and phosphodiester bonds in nucleotide triphosphates and oligonucleotides, respectively, to generate nucleoside 5'-monophosphates. The encoded protein is a type II transmembrane glycoprotein that negatively regulates bone mineralization. Mice harboring a nonsense mutation in this gene, termed tiptoe walking (ttw), exhibit ectopic ossification of the spinal ligaments. The encoded protein binds to the insulin receptor, inhibits downstream signaling events and induces insulin resistance and glucose tolerance. This gene is located adjacent to a paralog on chromosome 10. Alternative splicing results in multiple transcript variants encoding different isoforms.

Buffer: PBS with 0.01% thiomersal,50% glycerol,pH7.3.

Immunogen: Recombinant fusion protein of mouse Enpp1

Dilution: WB 1:500-1:2000;IF 1:50-1:200

Calculated MW: 103kDa

Observed MW: 120kDa/170kDa
More Information
SKU ELSE-AB-91948-200
Manufacturer Elabscience Biotechnology
Manufacturer SKU E-AB-91948-200
Package Unit 200μL
Quantity Unit STK
Reactivity Human, Mouse (Murine), Rat (Rattus)
Clonality Polyclonal
Application Immunofluorescence, Western Blotting
Isotype IgG
Host Rabbit
Conjugate Unconjugated
Product information (PDF) Download
MSDS (PDF) Download