EO 1428, CAS 321351-00-2

Product Description: EO 1428 is a highly specific inhibitor of p38 of the aminobenzophenone class. EO 1428 (1 μM ) markedly attenuates LPS-induced tumor necrosis factor α-converting enzyme (TACE) activity up-regulation[1].

Applications: COVID-19-immunoregulation

Formula: C20H16BrClN2O

References: [1]Alasdair J Scott, et al. Reactive oxygen species and p38 mitogen-activated protein kinase mediate tumor necrosis factor α-converting enzyme (TACE/ADAM-17) activation in primary human monocytes. J Biol Chem. 2011 Oct 14;286(41):35466-35476.

CAS Number: 321351-00-2

Molecular Weight: 415.71

Compound Purity: 99.65

Research Area: Inflammation/Immunology

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: p38 MAPK

• SKU: MEXHY-108647-10
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-108647-10
• Package Unit: 10 mg
• Quantity Unit: STK