Epifriedelanol, CAS 16844-71-6

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: (3ß,4ß,5ß,8a,9ß,10a,13a,14ß)-5,9,13-trimethyl-4,25,26-trinoroleanan-3-ol

Purity: ≥85%

Formula Markup: C30H52O

Formula Weight: 428.73328

CAS Number: 16844-71-6

Notes: Epifriedelanol is a triterpene that has been found in U. davidiana root bark and has anticancer and senescence modifying activities.{66087} It increases levels of P-glycoprotein (P-gp) and multidrug resistance protein 2 (MDR2) and enhances doxorubicin-induced cytotoxicity in doxorubicin-resistant K562/ADM cells when used at concentrations ranging from 5 to 20 µM. It also inhibits doxorubicin-induced senescence in isolated human dermal fibroblasts (HDFs), as well as replicative senescence in HDFs and human umbilical vein endothelial cells (HUVECs).{66088}

• SKU: CAY36148-10
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 36148-10
• Package Unit: 10 mg
• Quantity Unit: STK
• Application: Reinstoffe