Eprotirome, CAS 355129-15-6

Product Description: Eprotirome (KB2115) is a liver-selective thyroid hormone receptor (TR) agonist. KB2115 has modestly higher affinity for TRβ than for TRα. Eprotirome reduces low-density lipoprotein (LDL) cholesterol concentrations. Eprotirome can be used for dyslipidemias and obesity research[1][2].

Applications: Metabolism-sugar/lipid metabolism

Formula: C18H17Br2NO5

References: [1]Martagón AJ, et al. The amelioration of hepatic steatosis by thyroid hormone receptor agonists is insufficient to restore insulin sensitivity in ob/ob mice. PLoS One. 2015 Apr 7;10(4):e0122987./[2]Rosalba Senese, et al. Thyroid hormone metabolites and analogues. Endocrine. 2019 Oct;66(1):105-114.

CAS Number: 355129-15-6

Molecular Weight: 487.14

Compound Purity: 99.77

Research Area: Endocrinology; Metabolic Disease

Solubility: DMSO : 125 mg/mL (ultrasonic)

Target: Thyroid Hormone Receptor

• SKU: MEXHY-10473-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-10473-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK