Product Description: Eriodictyol is a flavonoid isolated from the Chinese herb, with antioxidant and anti-inflammatory activity. Eriodictyol induces Nrf2 signaling pathway. Eriodictyol is also a potent influenza RNA-dependent RNA polymerase inhibitor with an IC50 of 18 nM.
Applications: COVID-19-immunoregulation
Formula: C15H12O6
References: [3]Václav Zima, et al. Unraveling the Anti-Influenza Effect of Flavonoids: Experimental Validation of Luteolin and its Congeners as Potent Influenza Endonuclease Inhibitors. Eur J Med Chem. 22 August 2020, 112754./[1]Zhu GF, et al. Eriodictyol, a plant flavonoid, attenuates LPS-induced acute lung injury through its antioxidative and anti-inflammatory activity. Exp Ther Med. 2015 Dec;10(6):2259-2266. Epub 2015 Oct 23./[2]Jing X, et al. Eriodictyol Attenuates β-Amyloid 25-35 Peptide-Induced Oxidative Cell Death in Primary Cultured Neurons by Activation of Nrf2. Neurochem Res. 2015 Jul;40(7):1463-71.
CAS Number: 552-58-9
Molecular Weight: 288.25
Compound Purity: 99.55
Research Area: Infection; Inflammation/Immunology
Solubility: DMSO : 125 mg/mL (ultrasonic)/H2O : < 0.1 mg/mL
Target: DNA/RNA Synthesis;Endogenous Metabolite;Influenza Virus;Keap1-Nrf2
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