Product Description: Etiocholanolone (5β-Androsterone) is the excreted metabolite of testosterone and has anticonvulsant activity[1]. Etiocholanolone is a less potent?neurosteroid positive allosteric modulator?(PAM) of the GABAA?receptor than its?enantiomer form[2].
Applications: Neuroscience-Neuromodulation
Formula: C19H30O2
References: [1]Ping Li,et al. Natural and Enantiomeric Etiocholanolone Interact With Distinct Sites on the Rat alpha1beta2gamma2L GABAA Receptor. Mol Pharmacol. 2007 Jun;71(6):1582-90./[2]Dorota Zolkowska, et al. Anticonvulsant Potencies of the Enantiomers of the Neurosteroids Androsterone and Etiocholanolone Exceed Those of the Natural Forms. Psychopharmacology (Berl). 2014 Sep;231(17):3325-32.
CAS Number: 53-42-9
Molecular Weight: 290.44
Compound Purity: 99.31
Research Area: Neurological Disease
Solubility: DMSO : 50 mg/mL (ultrasonic;warming;heat to 60°C)