Shelf life (days): 1460.0
Formulation: A crystalline solid
Formal Name: 5-chloro-6'-methyl-3-[4-(methylsulfonyl)phenyl]-2,3'-bipyridine
Purity: ≥98%
Formula Markup: C18H15ClN2O2S
Formula Weight: 358.8
CAS Number: 202409-33-4
Notes: Etoricoxib is a dipyridinyl compound that demonstrates high in vitro and ex vivo selectivity for COX-2 over COX-1 in several assays, e.g., in the production of PGE2 by CHO cells expressing either COX-2 (IC50 = 79 nM) or COX-1 (IC50 > 50 µM).{11268,15425} Oral etoricoxib is well absorbed and metabolized extensively via oxidation, with metabolites excreted largely in the urine.{12837}