Product Description: Fadraciclib (CYC065) is a second-generation, orally available ATP-competitive inhibitor of CDK2/CDK9 kinases[1] with IC50s of 5 and 26 nM, respectively[2].
Applications: Cancer-Kinase/protease
Formula: C21H31N7O
References: [1]Cocco E, et al. Dual CCNE1/PIK3CA targeting is synergistic in CCNE1-amplified/PIK3CA-mutated uterine serous carcinomas in vitro and in vivo. Br J Cancer. 2016 Jul 26;115(3):303-11./[2]Sumana Devata, et al. Molecular markers and venous thromboembolism (VTE) in acute myelogenous leukemia (AML)
CAS Number: 1070790-89-4
Molecular Weight: 397.52
Compound Purity: 99.78
Research Area: Cancer
Solubility: DMSO : ≥ 100 mg/mL
Target: CDK