Product Description: Faropenem sodium is an orally bioavailable penem antibiotic. Faropenem sodium regulates inorganic phosphate transporter Npt1. Faropenem sodium inhibits M. tuberculosis (MIC of 1.3 μg/mL) and B. anthracis[1][2].
Applications: COVID-19-immunoregulation
Formula: C12H14NNaO5S
References: [1]Dhar N, et al. Rapid cytolysis of Mycobacterium tuberculosis by faropenem, an orally bioavailable β-lactam antibiotic. Antimicrob Agents Chemother. 2015 Feb;59(2):1308-19./[2]Uchino H, et al. Faropenem transport across the renal epithelial luminal membrane via inorganic phosphate transporter Npt1. Antimicrob Agents Chemother. 2000 Mar;44(3):574-7./[3]Gill SC, et al. Pharmacokinetic-pharmacodynamic assessment of faropenem in a lethal murine Bacillus anthracis inhalation postexposure prophylaxis model. Antimicrob Agents Chemother. 2010 May;54(5):1678-83.
CAS Number: 122547-49-3
Molecular Weight: 307.30
Compound Purity: 98.87
Research Area: Infection
Solubility: DMSO : 25 mg/mL (ultrasonic)/H2O : 100 mg/mL (ultrasonic)
Target: Antibiotic;Bacterial