Target Synonym: HBGF;FGF;BFGF;FGF-2;FGFB;HBGF-2;Basic FGF;FGF2;Basic Fibroblast Growth Factor;B-FGF;FGF-β;Fibroblast Growth Factor 2;heparin-binding growth factor 2;prostatropin;BFGF;B-FGF;FGF-2;FGFB;fibroblast growth factor 2;HBGF-2;heparin-binding growth factor 2;prostatropin;basic;Basic fibroblast growth factor bFGF;FGF 2;FGF B;FGF2 basic;Fibroblast growth factor;Fibroblast growth factor 2 (basic);HBGF 2;HBGF2;HBGH 2;HBGH2;Heparin binding growth factor 2 precursor;heparin-binding growth factor 2;FGF-β
Background: FGF basic, also known as FGF-2 and HBGF-2, is a member of the FGF family of mitogenic proteins. FGF basic is widely expressed and affects diverse aspects of embryonic development by regulating cell proliferation, differentiation, and survival. Various N-terminal extensions affect localization of FGF basic in cellular compartments but do not affect biological activity. Binding of FGF to heparin or cell surface heparan sulfate proteoglycans is necessary for binding of FGF to high affinity FGF receptors. Mature human FGF basic shares greater than 96% aa sequence identity with bovine, mouse, and rat FGF basic.
Immunogen: Recombinant Human FGF2 Protein
Buffer: 0.2 μm filtered solution in PBS
Dilution: WB 1:500-1:2000;
Calculated MW: 31 kDa
Observed MW: 17-30 kDa
English
Deutsch
