Product Description: FIIN-2 is an irreversible inhibitor of FGFR with an IC50 of 3.1, 4.3, 27, and 45 nM for FGFR1, FGFR2, FGFR3 and FGFR4, respectively.
Applications: Cancer-Kinase/protease
Formula: C35H38N8O4
References: [1]Tan L, et al. Development of covalent inhibitors that can overcome resistance to first-generation FGFR kinase inhibitors. Proc Natl Acad Sci U S A. 2014 Nov 11;111(45):E4869-4877.
CAS Number: 1633044-56-0
Molecular Weight: 634.73
Compound Purity: 99.32
Research Area: Cancer
Solubility: DMSO : ≥ 30 mg/mL
Target: FGFR