FIN56, CAS 1083162-61-1

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: N2,N7-dicyclohexyl-9-(hydroxyimino)-9H-fluorene-2,7-disulfonamide

Purity: ≥98%

Formula Markup: C25H31N3O5S2

Formula Weight: 517.66286

CAS Number: 1083162-61-1

Notes: FIN56 is an inducer of ferroptosis and a derivative of CIL56 (Item No. 19287).{39186} It selectively induces ferroptosis in BJ cells overexpressing oncogenic HRASG12V via acetyl-CoA carboxylase-dependent reduction in expression of GPX4 protein. This effect is reversed by the ferroptosis inhibitors deferoxamine (Item No. 14595) and α-tocopherol as well as overexpression of the fusion protein GFP-GPX4. FIN56 also binds to and activates squalene synthase in a GPX4 degradation-independent manner.

• SKU: CAY25180-50
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 25180-50
• Package Unit: 50 mg
• Quantity Unit: STK