Shelf life (days): 1460.0
Formulation: A solid
Formal Name: 8-cyano-1-cyclopropyl-6-fluoro-7-[(4aS,7aS)-hexahydropyrrolo[3,4-b]-1,4-oxazin-6(2H)-yl]-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid, monohydrochloride
Purity: ≥98%
Formula Markup: C20H19FN4O4 / HCl
Formula Weight: 434.9
CAS Number: 209342-41-6
Notes: Finafloxacin is a fluoroquinolone antibiotic.{32845} It is active against S. pneumoniae and P. aeruginosa, as well as methicillin-resistant S. aureus (MRSA) that is sensitive or resistant to fluoroquinolones (MIC90s = 2, 2, 0.125, and 4 mg/L, respectively). Finafloxacin (23.1 mg/kg) improves survival in F. tularensis- or Y. pestis-infected mice in models of tularemia or plague, respectively.{57902} Formulations containing finafloxacin have been used in the treatment of acute otitis externa.