Target Synonym: CD11 antigen-like family member B;CD11b;CR-3 alpha chain;Integrin alpha-M;Itgam;Leukocyte adhesion receptor MO1
Usage: Each lot of this antibody is quality control tested by flow cytometric analysis.
The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Storage: This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Citation Link 1:
https://789.bio/ec/WvPCWDCitation Link 2:
C57BL/6 murine bone marrow cells are stained with FITC Anti-Mouse/Human CD11b Antibody (filled gray histogram). Unstained bone marrow cells (empty black histogram) are used as control.Background: CD11b is a 170 kD glycoprotein also known as αM integrin, Mac-1 α subunit, Mol, CR3, and Ly-40. CD11b is a member of the integrin family, primarily expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b non-covalently associates with CD18 (β2 integrin) to form Mac-1. Mac-1 plays an important role in cell-cell interaction by binding its ligands ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, and fibrinogen.
Buffer: Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
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