Product Description: FITC-labeled ODN 1018 (sodium),an oligodeoxynucleotide, is a TLR-9 agonist. FITC-labeled ODN 1018 (sodium) can be used to evaluate CpG ODN cellular uptake and localization by confocal laser-scanning microscopy (excitation 495 nm, emission 520 nm) or flow cytometry.
Applications: COVID-19-immunoregulation
Formula: N/A
References: [1]Eng NF, et al. The potential of 1018 ISS adjuvant in hepatitis B vaccines: HEPLISAV™ review. Hum Vaccin Immunother. 2013 Aug;9(8):1661-72./[2]Friedberg JW, et al. Phase II study of a TLR-9 agonist (1018 ISS) with rituximab in patients with relapsed or refractory follicular lymphoma. Br J Haematol. 2009 Aug;146(3):282-91.
Molecular Weight: 8171.00
Compound Purity: 98.71
Research Area: Inflammation/Immunology
Solubility: 10 mM in H2O
Target: Toll-like Receptor (TLR)