FITM, CAS 932737-65-0

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: 4-fluoro-N-methyl-N-[4-[6-[(1-methylethyl)amino]-4-pyrimidinyl]-2-thiazolyl]-benzamide

Purity: ≥98%

Formula Markup: C18H18FN5OS

Formula Weight: 371.433023

CAS Number: 932737-65-0

Notes: FITM is an antagonist of metabotropic glutamate receptor 1 (mGluR1; IC50 = 5.1 nM for the human receptor).{46556} It is selective for mGluR1 over mGluR2, mGluR5, and mGluR8 (IC50s = >10, 7, and >10 µM, respectively). FITM (0.3 mg/kg) decreases methamphetamine-induced hyperlocomotion in mice and reverses disruptions in prepulse inhibition induced by methamphetamine and ketamine in rats when administered at a dose of 1 mg/kg.

• SKU: CAY29219-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 29219-5
• Package Unit: 5 mg
• Quantity Unit: STK