Fluorofenidone, CAS 848353-85-5

Description: Fluorofenidone (AKF-PD) attenuates the progression of renal interstitial fibrosis partly by suppressing NADPH oxidase and extracellular matrix (ECM) deposition via the PI3K/Akt signalling pathway. Fluorofenidone is an analogue of AMR69. Which displays equivalent lower toxicity, antifibrotic activity, and longer half-life.

CAS Number: 848353-85-5

Formula: C12H10FNO

Molecular Weight: 203,21

References: Qin J, et al. Fluorofenidone inhibits nicotinamide adeninedinucleotide phosphate oxidase via PI3K/Akt pathway in the pathogenesis of renal interstitial fibrosis. Nephrology (Carlton). 2013 Oct;18(10):690-9.

• SKU: TGMT15300-2mg
• Manufacturer: TargetMol Chemicals
• Manufacturer SKU: T15300-2mg
• Package Unit: 2 mg
• Quantity Unit: STK