Shelf life (days): 1460.0
Formulation: A crystalline solid
Formal Name: 4S-cyclohexyl-1-[2-[(R)-[(1S)-2-methyl-1-(1-oxopropoxy)propoxy](4-phenylbutyl)phosphinyl]acetyl]-L-proline, monosodium salt
Purity: ≥98%
Formula Markup: C30H45NO7P / Na
Formula Weight: 585.644371
CAS Number: 88889-14-9
Notes: Fosinopril is a prodrug form of the angiotensin converting enzyme (ACE) inhibitor fosinoprilat.{39303} Oral administration of fosinopril inhibits angiotensin I-induced pressor responses in normotensive rats, dogs, and monkeys when administered at doses of 15, 15, and 10 µmol/kg, respectively. Fosinopril (2.5 mg/kg) reduces fractional shortening and decreases left ventricular size in a porcine model of congestive heart failure.{39770} Formulations containing fosinopril have been used in the treatment of hypertension and congestive heart failure.
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