Furafylline, CAS 80288-49-9

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: 3-(2-furanylmethyl)-3,9-dihydro-1,8-dimethyl-1H-purine-2,6-dione

Purity: ≥95%

Formula Markup: C12H12N4O3

Formula Weight: 260.3

CAS Number: 80288-49-9

Notes: Furafylline is a selective inhibitor of human cytochrome P450 (CYP)1A2 (IC50 = 0.07 µM), demonstrating little effect on other CYP isoforms including 2D1, 2C, 3A, or 1A1.{25943} It was originally introduced as a bronchodilator with extended duration compared to theophylline, but then subsequently reported to inhibit the oxidation of caffeine (Item No. 14118), a reaction catalyzed by CYP1A2.{25943,25942}

• SKU: CAY9000058-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 9000058-5
• Package Unit: 5 mg
• Quantity Unit: STK