GAD65 blocking peptide

Species: Human

Specificity/Sensitivity: The peptide was used in the production of GTX89575.

Form: Lyophilized powder

Buffer (with preservative): Reconstitute with 200μl distilled water to obtain a 0.5mg/ml peptide solution. Lyophilized from 5% (v/v) acetonitrile/H₂O, no preservative.

Background: This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Oct 2008]

Region Sequence: C-TLEDNEERMSRLSK

Full Name: glutamate decarboxylase 2

• SKU: GTX89575-PEP-100
• Manufacturer: GeneTex
• Manufacturer SKU: GTX89575-PEP-100
• Package Unit: 100 μg
• Quantity Unit: STK
• Human Gene ID: 2572