GAK inhibitor 49, CAS 319492-82-5

Product Description: GAK inhibitor 49 is a potent, ATP-competitive and highly selective cyclin G associated kinase (GAK) inhibitor with a Ki of 0.54 nM and a cell IC50 of 56 nM. GAK inhibitor 49 also shows binding to RIPK2[1].

Applications: COVID-19-immunoregulation

Formula: C20H22N2O5

References: [1]Asquith CRM, et al. Identification and Optimization of 4-Anilinoquinolines as Inhibitors of Cyclin G Associated Kinase. ChemMedChem. 2018;13(1):48-66.

CAS Number: 319492-82-5

Molecular Weight: 370.40

Compound Purity: 98.79

Research Area: Infection

Solubility: DMSO : 50 mg/mL (ultrasonic;warming;heat to 80°C)

Target: Cyclin G-associated Kinase (GAK)

• SKU: MEXHY-124793-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-124793-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK