Gamcemetinib, CAS 1887069-10-4

Product Description: Gamcemetinib (CC-99677) is a potent, covalent, and irreversible inhibitor of the mitogen-activated protein (MAP) kinase-activated protein kinase-2 (MK2) pathway in both biochemical (IC50=156.3 nM) and cell based assays (EC50=89 nM). Gamcemetinib is extracted from patent WO2020236636, compound 1[1].

Applications: COVID-19-immunoregulation

Formula: C22H20ClN5O3S

References: [1]WO2020236636

CAS Number: 1887069-10-4

Molecular Weight: 469.94

Compound Purity: 99.06

Research Area: Inflammation/Immunology

Solubility: DMSO : 37.5 mg/mL (ultrasonic;warming;heat to 60°C)

Target: MAPKAPK2 (MK2)

• SKU: MEXHY-139504-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-139504-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK