Gandotinib, CAS 1229236-86-5

Product Description: Gandotinib (LY2784544) is a potent JAK2 inhibitor with IC50 of 3 nM. Gandotinib (LY2784544) also inhibits FLT3, FLT4, FGFR2, TYK2, and TRKB with IC50 of 4, 25, 32, 44, and 95 nM.

Applications: Cancer-Kinase/protease

Formula: C23H25ClFN7O

References: [1]Ma L, et al. Discovery and characterization of LY2784544, a small-molecule tyrosine kinase inhibitor of JAK2V617F. Blood Cancer J. 2013, 3, e109.

CAS Number: 1229236-86-5

Molecular Weight: 469.94

Compound Purity: 99.58

Research Area: Cancer

Solubility: DMSO : 33.33 mg/mL (ultrasonic)

Target: FGFR;FLT3;JAK;VEGFR

• SKU: MEXHY-13034-5
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-13034-5
• Package Unit: 5 mg
• Quantity Unit: STK