Product Description: Ganoderic acid C2 is a bioactive triterpenoid in Ganoderma lucidum. Ganoderic acid C2 possesses the potential anti-tumor bioactivity, antihistamine, anti-aging and cytotoxic effects. Ganoderic acid C2 is the inhibitor for aldose reductase with an IC50 of 43.8 µM[1][2].
Applications: Cancer-programmed cell death
Formula: C30H46O7
References: [1]Guo XY, et al. l characterization of minor metabolites and pharmacokinetics of ganoderic acid C2 in rat plasma by HPLC coupled with electrospray ionization tandem mass spectrometry. J Pharm Biomed Anal. 2013 Mar 5;75:64-73./[2]Fatmawati S, et al. Inhibition of aldose reductase in vitro by constituents of Ganoderma lucidum. Planta Med. 2010 Oct;76(15):1691-3./[3]Liu Y, et al., Ganoderic acid C2 exerts the pharmacological effects against cyclophosphamide-induced immunosuppression: a study involving molecular docking and experimental validation. Sci Rep. 2023 Oct 18;13(1):17745.
CAS Number: 103773-62-2
Molecular Weight: 518.68
Compound Purity: 99.72
Research Area: Cancer; Inflammation/Immunology
Solubility: DMSO : 50 mg/mL (ultrasonic)
Target: Aldose Reductase
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