Gardiquimod, CAS 1020412-43-4

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: 4-amino-2-[(ethylamino)methyl]-a,a-dimethyl-1H-imidazo[4,5-c]quinoline-1-ethanol

Purity: ≥95%

Formula Markup: C17H23N5O

Formula Weight: 313.4

CAS Number: 1020412-43-4

Notes: Gardiquimod is an agonist of human toll-like receptor 7 (TLR7), but not human TLR8, although it activates both porcine TLR7 and TLR8.{31200} At 0.5 to 2 µg/ml, it enhances the immunosuppressive activity of T regulatory cells.{31198} Gardiquimod is effective as a mucosal adjuvant for Norwalk virus-like particles and inhibits infection of macrophages and T cells by HIV-1.{31199,31197} It inhibits proliferation and migration while inducing apoptosis in pancreatic cancer cells in vitro.{31201}

• SKU: CAY18877-50
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 18877-50
• Package Unit: 50 mg
• Quantity Unit: STK