Product Description: GCase modulator-1 (compound 9g), a derivative of Quinazoline, is a modulator of GCase (Glucosidase) (AC50=2.23 μM)[1].
Applications: Cancer-programmed cell death
Formula: C22H18N4
References: [1]Zheng J, et al. Conversion of Quinazoline Modulators from Inhibitors to Activators of β-Glucocerebrosidase. J Med Chem. 2019 Feb 14;62(3):1218-1230.
CAS Number: 796079-91-9
Molecular Weight: 338.41
Compound Purity: 97.0
Research Area: cancer
Solubility: DMSO : 20 mg/mL (ultrasonic;warming;heat to 60°C)