Clone Name: 10A3
Application Note: WB: 1:500 - 1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 34
Form: Liquid
Buffer (with preservative): PBS, no preservative.
Concentration: Batch dependent (Please refer to the vial label for the specific concentration.)
Background: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. The protein is expressed in a broad range of cell types, acts as a pleiotropic cytokine and is involved in the stress response program of cells after cellular injury. Increased protein levels are associated with disease states such as tissue hypoxia, inflammation, acute injury and oxidative stress. [provided by RefSeq, Aug 2016]
Uniprot ID: Q99988
Antigen Species: Human
Immunogen: Human recombinant GDF15.
Purification: Protein G purified
Conjugation: Unconjugated
Full Name: growth differentiation factor 15
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