Product Description: GDP-L-fucose is a nucleotide sugar that is a key substrate for the biosynthesis of fucose oligosaccharides, providing the fucose moiety for the oligosaccharides.The formation of GDP-L-fucose occurs through two pathways, the major ab initio metabolic pathway and the minor remedial metabolic pathway. GDP-L-fucose is associated with diabetes in rats[1][2].
Applications: Metabolism-sugar/lipid metabolism
Formula: C16H25N5O15P2
References: [1]Weiyang Wang, et al. Cell-free enzymatic synthesis of GDP-L-fucose from mannose. AMB Express. 2019 May 27;9(1):74./[2]1.Wiese TJ, et al. Effect of L-fucose and D-glucose concentration on L-fucoprotein metabolism in human Hep G2 cells and changes in fucosyltransferase and alpha-L-fucosidase activity in liver of diabetic rats. Biochim Biophys Acta. 1997 Apr 17;1335(1-2):61-72.
CAS Number: 15839-70-0
Molecular Weight: 589.34
Compound Purity: 99.78
Research Area: Metabolic Disease
Solubility: H2O : 250 mg/mL (ultrasonic)
Target: Endogenous Metabolite
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