Conjugation: FITC: Fluorescein Isothiocyanate
Description of Target: The Rho family of small GTPases act as molecular switches to control a wide range of cellular processes. Guanine nucleotide exchange factors (GEFs), like GEFT, activate Rho GTPases by accelerating GDP/GTP exchange.The Rho family of small GTPases act as molecular switches to control a wide range of cellular processes. Guanine nucleotide exchange factors (GEFs), like GEFT, activate Rho GTPases by accelerating GDP/GTP exchange (Souchet et al., 2002 [PubMed 11861769]).[supplied by OMIM].
Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human GEFT
Key Reference: Lutz,S., (2007) Science 318 (5858), 1923-1927
Molecular Weight: 64kDa
Peptide Sequence: Synthetic peptide located within the following region:
RLGDQAQGSTHTPINGSLPSLLLSPKGEVARALLPLDKQALGDIPQAPHDProduct Format: Liquid. Purified antibody supplied in 1x PBS buffer.
Protein Name: Rho guanine nucleotide exchange factor 25
Protein Size: 580
Purification: Affinity Purified
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