Description: Gelsevirine, a novel STING-specific inhibitor, is an alkaloid from Gelsemium elegans with anxiolytic and antiproliferative activities that inhibits interferon and inflammatory cytokine induction in macrophages exposed to STING agonists, and attenuates STING-related inflammation in sepsis.
CAS Number: 38990-03-3
Formula: C21H24N2O3
Molecular Weight: 352,43
References: Chen Y,et al. Gelsevirine is a novel STING-specific inhibitor and mitigates STING-related inflammation in sepsis. Front Immunol. 2023 Jul 31;14:1190707.