GITR antibody (7R12)

Clone Name: 7R12

Application Note: WB: 1:500 - 1:1000. FCM: 1:50 - 1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Calculated MW: 26

Form: Liquid

Buffer (with preservative): PBS, no preservative.

Concentration: 500 μg/ml (Please refer to the vial label for the specific concentration.)

Background: This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Feb 2011]

Uniprot ID: Q9Y5U5

Antigen Species: Human

Immunogen: Human recombinant TNFRSF18 EC domain

Purification: Protein G purified

Conjugation: Unconjugated

Full Name: TNF receptor superfamily member 18

• SKU: GTX52766-50
• Manufacturer: GeneTex
• Manufacturer SKU: GTX52766-50
• Package Unit: 50 μg
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Monoclonal
• Application: Western Blotting, Flow Cytometry, Neutralization, Inhibition
• Isotype: IgG1
• Human Gene ID: 8784
• Host: Mouse
• Conjugate: Unconjugated