GK921, CAS 1025015-40-0

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: 3-(2-phenylethynyl)-2-[2-(1-pyrrolidinyl)ethoxy]-pyrido[2,3-b]pyrazine

Purity: ≥98%

Formula Markup: C21H20N4O

Formula Weight: 344.40986

CAS Number: 1025015-40-0

Notes: GK921 is an inhibitor of transglutaminase 2 (TG2; IC50 = 7.71 µM).{60621} It is cytotoxic against a panel of eight renal cell carcinoma (RCC) cell lines (mean GI50 = 0.905 µM). GK921 (8 mg/kg) suppresses tumor growth in ACHN and Caki-1 RCC mouse xenograft models.

• SKU: CAY34359-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 34359-5
• Package Unit: 5 mg
• Quantity Unit: STK