Product Description: Glecaprevir is a novel HCV NS3/4A protease inhibitor, with IC50 values ranging from 3.5 to 11.3 nM. Glecaprevir is also a SARS-CoV 3CLpro inhibitor with an IC50 of 4.09 μM[2].
Applications: COVID-19-anti-virus
Formula: C38H46F4N6O9S
References: [1]Ng TI, et al. In Vitro Antiviral Activity and Resistance Profile of the Next-Generation Hepatitis C Virus NS3/4A Protease Inhibitor Glecaprevir. Antimicrob Agents Chemother. 2017 Oct 30. pii: AAC.01620-17./[2]Qi Sun, et al. Bardoxolone and bardoxolone methyl, two Nrf2 activators in clinical trials, inhibit SARS-CoV-2 replication and its 3C-like protease. Signal Transduct Target Ther. 2021 May 29;6(1):212.
CAS Number: 1365970-03-1
Molecular Weight: 838.87
Compound Purity: 99.93
Research Area: Infection
Solubility: DMSO : ≥ 83.3 mg/mL
Target: HCV;HCV Protease;SARS-CoV
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