GLI antagonist-1, CAS 599150-20-6

Product Description: GLI antagonist-1 is a potent GLI antagonist with an IC50 value of 1.1 μM. GLI antagonist-1 shows anti-proliferative activity. GLI antagonist-1 decreases the GLI1 mRNA expression. GLI antagonist-1 inhibits colony formation in a dose-dependent manner[1].

Applications: Cancer-programmed cell death

Formula: C27H29NO6

References: [1]Oladapo HO, et al. Pharmacological targeting of GLI1 inhibits proliferation, tumor emboli formation and in vivo tumor growth of inflammatory breast cancer cells. Cancer Lett. 2017 Dec 28;411:136-149.

CAS Number: 599150-20-6

Molecular Weight: 463.53

Compound Purity: 95

Research Area: Cancer

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: Gli

• SKU: MEXHY-107551-10
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-107551-10
• Package Unit: 10 mg
• Quantity Unit: STK