GNE 2861, CAS 1394121-05-1

Product Description: GNE 2861 is a PAK inhibitor that displays group II selectivity. GNE 2861 inhibits PAK4, PAK5 and PAK6 with IC50s of 7.5, 36, 126 nM, respectively.

Applications: Cancer-Kinase/protease

Formula: C22H26N6O2

References: [1]Karpov AS, et al. Optimization of a Dibenzodiazepine Hit to a Potent and Selective Allosteric PAK1 Inhibitor. ACS Med Chem Lett. 2015 May 22;6(7):776-81.

CAS Number: 1394121-05-1

Molecular Weight: 406.48

Compound Purity: 99.20

Research Area: Cancer

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: PAK

• SKU: MEXHY-12632-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-12632-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK