GNE 6901, CAS 1698900-69-4

Product Description: GNE 6901 (compound 40) is a potent GluN2A-selective NMDAR positive allosteric modulator (PAM) with an EC50 of 382 nM[1].

Applications: Neuroscience-Neurodegeneration

Formula: C18H17FN2O3S

References: [1]Matthew Volgraf, et al. Discovery of GluN2A-Selective NMDA Receptor Positive Allosteric Modulators (PAMs): Tuning Deactivation Kinetics via Structure-Based Design. J Med Chem. 2016 Mar 24;59(6):2760-79. /[2]Matthew Volgraf, et al. Discovery of GluN2A-Selective NMDA Receptor Positive Allosteric Modulators (PAMs): Tuning Deactivation Kinetics via Structure-Based Design. J Med Chem. 2016 Mar 24;59(6):2760-79.

CAS Number: 1698900-69-4

Molecular Weight: 360.40

Research Area: Neurological Disease

Solubility: 10 mM in DMSO

Target: iGluR

• SKU: MEXHY-107423-25
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-107423-25
• Package Unit: 25 mg
• Quantity Unit: STK