GNE-7915, CAS 1351761-44-8

Product Description: GNE-7915 is a potent, selective and brain-penetrant inhibitor of LRRK2 with an IC50 of 9 nM.

Applications: Neuroscience-Neuromodulation

Formula: C19H21F4N5O3

References: [1]Kavanagh ME, et al. The development of CNS-active LRRK2 inhibitors using property-directed optimisation. Bioorg Med Chem Lett.?2013 Jul 1;23(13):3690-6./[2]Estrada AA, et al. Discovery of highly potent, selective, and brain-penetrable leucine-rich repeat kinase 2 (LRRK2) small molecule inhibitors. J Med Chem. 2012 Nov 26;55(22):9416-33.

CAS Number: 1351761-44-8

Molecular Weight: 443.40

Compound Purity: 99.82

Research Area: Neurological Disease

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: LRRK2

• SKU: MEXHY-18163-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-18163-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK