Goat anti-SA2 Antibody, Affinity Purified

Stock Concentration: 1000 µg/ml

Conjugate Type: Unconjugated

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide

Shelf Life: 1 year from date of receipt

Protein ID: NP_006594.3

Uniprot ID: Q8N3U4

Background: SA2 is a component of the multisubunit cohesin complex. Cohesin functions to hold sister chromatids together during meiosis and mitosis and ensure proper segregation of chromosomes. Cohesin must dissociate from sister chromatids during prophase and metaphase so that they can segregate to opposite poles of the cell during anaphase. As part of the cohesin complex, SA2 appears to play a role in cohesin dissociation required for sister chromatid separation. Interestingly, SA2 has been demonstrated to also exhibit transcriptional regulatory activity through an association with NF-kappaB.

Immunogen: Between 1100 and 1150

• SKU: BEYA300-158A
• Manufacturer: Bethyl Laboratories
• Manufacturer SKU: A300-158A
• Package Unit: 100 µl
• Quantity Unit: STK
• Reactivity: Human, Mouse (Murine)
• Clonality: Polyclonal
• Application: Western Blotting, Immunocytochemistry, Simple Western™ validated
• Isotype: Whole IgG
• Human Gene ID: 10735
• Host: Goat
• Conjugate: Unconjugated