Golvatinib, CAS 928037-13-2

Product Description: Golvatinib (E-7050) is a potent dual inhibitor of both c-Met and VEGFR2 kinases with IC50s of 14 and 16 nM, respectively.

Applications: Cancer-Kinase/protease

Formula: C33H37F2N7O4

References: [1]Nakagawa T et al. E7050: a dual c-Met and VEGFR-2 tyrosine kinase inhibitor promotes tumor regression and prolongs survival in mouse xenograft models. Cancer Sci, 2010, 101(1), 210-215./[2]Wang W et al. Met kinase inhibitor E7050 reverses three different mechanisms of hepatocyte growth factor-induced tyrosine kinase inhibitor resistance in EGFR mutant lung cancer. Clin Cancer Res, 2012, 18(6), 1663-1671.

CAS Number: 928037-13-2

Molecular Weight: 633.69

Compound Purity: 99.86

Research Area: Cancer

Solubility: DMSO : 50 mg/mL (ultrasonic)

Target: c-Met/HGFR;VEGFR

• SKU: MEXHY-13068-5
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-13068-5
• Package Unit: 5 mg
• Quantity Unit: STK