GPX4 Activator 2, CAS 950365-31-8

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: N-(2,4-dimethoxyphenyl)-1-[5-(4-methyl-1-piperazinyl)-1,3,4-thiadiazol-2-yl]-1H-pyrrole-2-methanamine

Purity: ≥98%

Formula Markup: C20H26N6O2S

Formula Weight: 414.528

CAS Number: 950365-31-8

Notes: A GPX4 ligand (Kd = 0.426 µM); inhibits erastin-induced ferroptosis in HT-1080 fibrosarcoma cells (EC50 = 7.8 µM); prevents erastin-induced increases in lipid peroxide levels in HT-1080 cells at 10 µM; decreases serum and cardiac levels of MDA and cardiac levels of Ast and reduces myocardial cell degeneration in a mouse model of doxorubicin-induced myocardial injury at 25 mg/kg

• SKU: CAY43195-10
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 43195-10
• Package Unit: 10 mg
• Quantity Unit: STK