GS-9901, CAS 1640247-87-5

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: 2,4-diamino-6-[[(S)-[5-chloro-8-fluoro-3,4-dihydro-4-oxo-3-(3-pyridinyl)-2-quinazolinyl]cyclopropylmethyl]amino]-5-pyrimidinecarbonitrile

Purity: ≥98%

Formula Markup: C22H17ClFN9O

Formula Weight: 477.9

CAS Number: 1640247-87-5

Notes: A PI3Kδ inhibitor (IC50 = 1 nM); selective for PI3Kδ over PI3Kα, PI3Kβ, and PI3Kγ (IC50s = 750, 100, and 190 nM, respectively) and a panel of 456 additional kinases, including 11 lipid and 56 mutant kinases, at 10 µM; activates basophils in isolated human whole blood (EC50 = 1 nM); decreases ankle swelling and disease severity in a rat model of collagen-induced arthritis at 1 and 3 mg/kg

• SKU: CAY42105-5
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 42105-5
• Package Unit: 5 mg
• Quantity Unit: STK