GSK126, CAS 1346574-57-9

Product Description: GSK126 (GSK2816126A) is a potent, highly selective inhibitor of EZH2 methyltransferase with an IC50 of 9.9 nM[1].

Applications: Cancer-programmed cell death

Formula: C31H38N6O2

References: [1]McCabe MT, et al. EZH2 inhibition as a therapeutic strategy for lymphoma with EZH2-activating mutations. Nature. 2012 Dec 6;492(7427):108-12./[2]Sato T, et al. PRC2 overexpression and PRC2-target gene repression relating to poorer prognosis in small cell lung cancer. Sci Rep. 2013 May 29;3:1911.

CAS Number: 1346574-57-9

Molecular Weight: 526.67

Compound Purity: 99.98

Research Area: Cancer

Solubility: DMSO : 12.5 mg/mL (ultrasonic)

Target: Histone Methyltransferase

• SKU: MEXHY-13470-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-13470-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK