GSK2334470, CAS 1227911-45-6

Product Description: GSK2334470 is a highly specific and potent inhibitor of PDK1 with an IC50 of 10 nM.

Applications: Cancer-Kinase/protease

Formula: C25H34N8O

References: [1]Najafov A, et al. Characterization of GSK2334470, a novel and highly specific inhibitor of PDK1. Biochem J.?2011 Jan 15;433(2):357-69./[2]Qi L, et al. PDK1-mTOR signaling pathway inhibitors reduce cell proliferation in MK2206 resistant neuroblastoma cells. Cancer Cell Int.?2015 Sep 29;15:91./[3]Scortegagna M, et al. Genetic inactivation or pharmacological inhibition of Pdk1 delays development and inhibits metastasis of Braf(V600E)::Pten(-/-) melanoma. Oncogene. 2014 Aug 21;33(34):4330-9.

CAS Number: 1227911-45-6

Molecular Weight: 462.59

Compound Purity: 99.78

Research Area: Cancer

Solubility: DMSO : ≥ 50 mg/mL

Target: PDK-1

• SKU: MEXHY-14981-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-14981-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK