Product Description: GSK2879552 dihydrochloride an orally active, selective and irreversible inhibitor of lysine specific demethylase 1 (LSD1/KDM1A), with potential antineoplastic activity[1][2].
Applications: Cancer-programmed cell death
Formula: C23H30Cl2N2O2
References: [1]Huang M, et al. Targeting KDM1A attenuates Wnt/β-catenin signaling pathway to eliminate sorafenib-resistant stem-like cells in hepatocellular carcinoma. Cancer Lett. 2017 Apr 2;398:12-21./[2]Mohammad HP, et al. A DNA Hypomethylation Signature Predicts Antitumor Activity of LSD1 Inhibitors in SCLC. Cancer Cell. 2015 Jul 13;28(1):57-69.
CAS Number: 1902123-72-1
Molecular Weight: 437.40
Compound Purity: 99.19
Research Area: Cancer
Solubility: DMSO : 31.25 mg/mL (ultrasonic)/H2O : 100 mg/mL (ultrasonic)
Target: Histone Demethylase