GSK3179106, CAS 1627856-64-7

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: 4-(4-ethoxy-1,6-dihydro-6-oxo-3-pyridinyl)-2-fluoro-N-[5-(2,2,2-trifluoro-1,1-dimethylethyl)-3-isoxazolyl]-benzeneacetamide

Purity: ≥98%

Formula Markup: C22H21F4N3O4

Formula Weight: 467.4

CAS Number: 1627856-64-7

Notes: GSK3179106 is an inhibitor of rearranged during transfection (RET) kinase (IC50 = 0.4 nM).{45511} It is selective for RET kinase over VEGF receptor 2 (VEGFR2/KDR; IC50 = 109 nM). GSK3179106 reduces the number of abdominal contractions induced by colorectal distension in acetic acid-sensitized rats when administered at a dose of 10 mg/kg twice per day.

• SKU: CAY24023-1
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 24023-1
• Package Unit: 1 mg
• Quantity Unit: STK