Shelf life (days): 1460.0
Formulation: A solid
Formal Name: 3-(2-(methoxy-d3)phenoxy)propane-1,2-diol
Purity: ≥99% deuterated forms (d1-d3)
Formula Markup: C10H11D3O4
Formula Weight: 201.23394
CAS Number: 1189924-85-3
Notes: Guaifenesin-d3 is intended for use as an internal standard for the quantification of guaifenesin (Item No. 21250) by GC- or LC-MS. Guaifenesin is an expectorant.{33409} It inhibits production of mucin 5AC (MUC5AC), reduces mucus viscosity and elasticity, and increases the mucociliary transport rate of endogenous particles in primary human tracheobronchial epithelial cells in a concentration-dependent manner.{60261} Guaifenesin (50 mg/kg, p.o.) increases phenol red secretion, a marker of expectorant activity, in rats.{60262} Formulations containing guaifenesin have been used as expectorants in the treatment of the common cold and chronic bronchitis.
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