GW 803430, CAS 515141-51-2

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: 6-(4-chlorophenyl)-3-[3-methoxy-4-[2-(1-pyrrolidinyl)ethoxy]phenyl]-thieno[3,2-d]pyrimidin-4(3H)-one

Purity: ≥98%

Formula Markup: C25H24ClN3O3S

Formula Weight: 482.0

CAS Number: 515141-51-2

Notes: GW 803430 is an antagonist of melanin-concentrating hormone receptor 1 (MCH1; IC50 = 0.5 nM).{45224} It reduces cumulative body weight and food intake in diet-induced obese rats when administered at doses of 1 and 3 mg/kg.{45225} GW 803430 (10 and 30 mg/kg) decreases marble-burying behavior in mice, indicating anxiolytic activity, but does not affect performance in the rotorod test. It also reduces immobility time in the forced swim and tail suspension tests in mice at doses of 3 and 10 mg/kg, respectively, indicating antidepressant-like activity.

• SKU: CAY13948-10
• Manufacturer: Cayman Chemical
• Manufacturer SKU: 13948-10
• Package Unit: 10 mg
• Quantity Unit: STK