GW-870086, CAS 827319-43-7

Product Description: GW-870086 is a potent anti-inflammatory agent, acting as a glucocorticoid receptor agonist, with a pIC50 of 10.1 in A549 cells expressing NF-κB.

Applications: Metabolism-sugar/lipid metabolism

Formula: C31H39F2NO6

References: [1]Uings IJ, et al. Discovery of GW870086: a potent anti-inflammatory steroid with a unique pharmacological profile. Br J Pharmacol. 2013 Jul;169(6):1389-403./[2]Stamer WD, et al. Unique response profile of trabecular meshwork cells to the novel selective glucocorticoid receptor agonist, GW870086X. Invest Ophthalmol Vis Sci. 2013 Mar 1;54(3):2100-7.

CAS Number: 827319-43-7

Molecular Weight: 559.64

Compound Purity: 99.59

Research Area: Inflammation/Immunology; Endocrinology

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: Glucocorticoid Receptor

• SKU: MEXHY-103662-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-103662-10.1
• Package Unit: 10 mM/1 ml
• Quantity Unit: STK